DMAE started out being known as a brain vitamin among university students and parents of children with ADD. But now it's known as the anti-sagging supplement because of its ability to stimulate facial muscles to remain more contracted while resting! TwinLabs Liquid DMAE Drops You can put this in your water when you are sick of taking pills. A dropperful provides 100mg of DMAE. BioChem Country Life DMAE Capsules - 260mg of DMAE, with B6, B5 - This made a difference! See All the DMAE Options Here While DMAE's reputation as a supplement is for being an anti-aging brain food, let's set the record straight first before talking about how much I love it! Studies have so far shown no improvement in Alzheimer's patients taking DMAE. While a study done on patients with "age-related mental decline" taking DMAE showed less depression, less anxiety, and increased motivation, the bad news is: no improvement in memory in that study. But Dr. Perricone, the famed dermatologist, thinks that if we take DMAE orally or eat it in food it could, indeed, have an effect on our memory. He says that a diet rich in DMAE will not only improve memory, but it will help us think more clearly and improve problem-solving abilities. DMAE helps to make acetylcholine, often called the memory neurotransmitter. Acetylcholine allows a nerve to commnicate with a muscle which causes the muscle to contract. When you send the message to your body to move, the signal goes from the brain, along a nerve until it stops just short of the muscle where there is a little reservoir of chemicals like acetylcholine. Acetylcholine is released and causes the muscle to contract. Since our levels of acetylcholine decline as we age, we can improve this process, tone our sagging face and body muscles, by raising our levels of acetylcholine. Eating and taking more DMAE (and choline) is the best way to raise acetylcholine levels. Meanwhile, just about everyone who takes DMAE notices an increase in focus, concentration and alertness. And it always feels good when you can work well and easily, which may explain some of the additional reports of an improvement in sense of well-being. DMAE was touted for a long time as a natural alternative to Ritlin, the ADD drug. Because you can have difficulty falling asleep at night - from all that focus! - it's best to take it early in the day and to start with 50mg to 150 mg. DMAE, dimethyl-amino-ethanol, is sold in Europe as Deanol.